Kashkadarya region is one of the most environmentally friendly, located in the basin of the Kashkadarya river. The toponym Kashkadarya has several meanings: "river lost in the sand" and "transparent, clean river".

The administrative center of the region is the city of Karshi, which celebrated its 2700th anniversary in 2006.

Due to the continental climate (sometimes even subtropical) on the slope of the Pamir-Alai mountains, the air in the region is the purest, and the natural landscape fascinates with its flora and fauna. There are several well – known nature reserves in the region - Kitab, Gissar and Kizil-say nature reserve.

It is here in the foothills that the colorful jewels of nature are grown-pomegranates, quinces, peaches, pears, cherries, lemons. Huge abundance of vegetables, several types of nuts: pistachios, peanuts, walnuts. Spacious pastures allow you to raise livestock. And all this under the warm sun, among wide fields and ancient mounds.

In addition to the excellent ecology and beautiful nature, the region is rich in ancient cities and architectural monuments. The birthplace of the outstanding commander Amir Timur - the city of Shakhrisabz in Kashkadarya region is listed as a UNESCO World Cultural heritage.

The region is located in the Kashkadarya river basin, on the western slope of the Pamir-Alai mountains.